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Posaconazole Injection (POSACONAZOLE - INJECTION)

This medicine is used for the following purposes:

  • prevent infection
  • infections caused by fungus
  • infections caused by yeast

Brand Name(s): Noxafil

Generic Name: Posaconazole

Instructions

This medicine is given as an IV injection into a vein.

This medicine should be given over 90 minutes.

Always inspect the medicine before using.

The liquid should be clear or light yellow.

Do not use the medicine if it contains any particles or if it has changed color.

Keep this medicine in the refrigerator. Do not freeze.

Speak with your nurse or pharmacist about how long the medicine can be stored safely at room temperature or in the refrigerator before it needs to be discarded.

Never use any medicine that has expired.

Discard unused diluted medicine after 24 hours.

Please ask your doctor, nurse, or pharmacist how to discard unused medicines safely.

Space doses evenly to keep a steady amount of medicine in the body.

Tell your doctor if you have severe or persistent sweating, diarrhea or vomiting. These can increase your risk of a serious side effect.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Tell your doctor if symptoms do not get better or if they get worse.

Keep using this medicine for the full number of days that it is prescribed. Do not stop the medicine even if you start to feel better.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

This medicine has been associated with a rare but serious skin rash. If you notice any red, peeling or blistered skin, contact your doctor immediately.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

This medicine is associated with a rare, but serious problem of the liver. Speak to your doctor about the early signs of liver problems and the benefits and risks of using this medicine.

Do not use the medication any more than instructed.

Your ability to stay alert or to react quickly may be impaired by this medicine. Do not drive or operate machinery until you know how this medicine will affect you.

Please check with your doctor before drinking alcohol while on this medicine.

Contact your doctor if you develop any signs of a new infection such as fever, cough, sore throat, or chills.

Tell the doctor or pharmacist if you are pregnant, planning to be pregnant, or breastfeeding.

Call your doctor right away if you notice any unusual bleeding or bruising.

If you have had a heart attack or a stroke within the past 6 months, talk to your doctor before using this medicine.

Ask your pharmacist how to properly throw away used needles or syringes.

Do not share this medicine with anyone who has not been prescribed this medicine.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • agitated feeling or trouble sleeping
  • diarrhea
  • dizziness
  • headaches
  • nausea and vomiting
  • stomach upset or abdominal pain

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • bleeding or bruising
  • changes in memory, mood, or thinking
  • swelling of the legs, feet, and hands
  • fainting
  • fever or chills
  • fast or irregular heart beats
  • pain, redness, swelling near injection
  • signs of liver damage (such as yellowing of eye or skin, dark urine, or unusual tiredness)
  • muscle cramps
  • red, burning, or itchy skin
  • shortness of breath
  • sore throat
  • persistent or unusual thirst
  • increased urinary frequency
  • vaginal bleeding or spotting between periods

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.

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