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galcanezumab

Pronunciation: GAL ka NEZ ue mab

Brand: Emgality Prefilled Pen, Emgality Prefilled Syringe

What is the most important information I should know about galcanezumab?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

What is galcanezumab?

Galcanezumab is used to prevent migraine headaches in adults.

Galcanezumab is also used to treat cluster headache episodes in adults.

Galcanezumab may also be used for purposes not listed in this medication guide.

What should I discuss with my healthcare provider before using galcanezumab?

You should not use galcanezumab if you are allergic to it.

Galcanezumab is not approved for use by anyone younger than 18 years old.

Tell your doctor if you are pregnant. It is not known whether this medicine will harm an unborn baby. However, having migraine headaches during pregnancy may cause preeclampsia (dangerously high blood pressure that can lead to medical problems in both mother and baby). The benefit of preventing migraines may outweigh any risks to the baby.

It may not be safe to breast-feed while using this medicine. Ask your doctor about any risk.

How should I use galcanezumab?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Galcanezumab is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.

For prevention of migraine headaches: Galcanezumab is usually given as a first dose of 2 injections, followed by 1 injection once per month.

For treatment of a cluster headache episodes: Galcanezumab is usually given as 3 injections at the start of the cluster period, followed by 1 injection once per month until the end of the cluster period.

Follow your doctor's dosing instructions very carefully.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you don't understand all instructions.

Prepare an injection only when you are ready to give it. Do not use if the medicine looks cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.

Store galcanezumab in its original carton in the refrigerator, protected from light. Do not freeze or shake the medicine.

You may briefly store galcanezumab at room temperature. Protect from light and use the medicine within 7 days. Do not put it back in the refrigerator.

Take the medicine out of the refrigerator and let it reach room temperature for 30 minutes before injecting your dose. Do not warm the medicine with hot water, sunlight, or a microwave.

Each prefilled syringe or pen is for one use only. Throw it away after one use, even if there is still medicine left inside.

What happens if I miss a dose?

Use the medicine as soon as you remember, and then restart your regular injection schedule 1 month later. Do not use two doses at one time to make up a missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using galcanezumab?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What are the possible side effects of galcanezumab?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

An allergic reaction to galcanezumab can occur several days after an injection.

Common side effects may include:

  • pain, redness, itching, or irritation where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect galcanezumab?

Other drugs may affect galcanezumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information?

Your pharmacist can provide more information about galcanezumab.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2019 Cerner Multum, Inc. Version: 2.01. Revision date: 6/13/2019.

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