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ioversol

Pronunciation: eye oh VERS ol

Brand: Optiray 240, Optiray 300, Optiray 320, Optiray 350

What is the most important information I should know about ioversol?

You should not be treated with this medicine if you have symptoms of an overactive thyroid. Tell your doctor if you have ever had any type of reaction to another contrast agent.

What is ioversol?

Ioversol is a radiopaque (RAY dee oh payk) contrast agent. Ioversol contains iodine, a substance that absorbs x-rays. Contrast agents are used to allow blood vessels, organs, and other non-bony tissues to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

Ioversol is used to help diagnose certain disorders of the heart, brain, and blood vessels.

Ioversol may also be used for purposes not listed in this medication guide.

What should I discuss with my health care provider before receiving ioversol?

You should not be treated with ioversol if you are allergic to it, or if you have:

  • symptoms of an overactive thyroid.

Tell your doctor if you have ever had:

  • any type of reaction to another contrast agent
  • liver or kidney disease;
  • a stroke, blood clot, or coronary artery disease (hardened arteries);
  • a seizure;
  • heart disease, high blood pressure, congestive heart failure;
  • diabetes;
  • homocystinuria;
  • sickle cell anemia;
  • asthma, hay fever, food allergies;
  • multiple myeloma (bone cancer);
  • pheochromocytoma (tumor of the adrenal gland);
  • a thyroid disorder; or
  • if you are dehydrated.

Ioversol is not expected to harm an unborn baby. Tell your doctor if you are pregnant.

It is not known whether ioversol passes into breast milk or if it could harm a nursing baby. If you choose not to expose your baby to any ioversol in your breast milk, do not breast-feed for 8 hours after you receive this medicine. If you use a breast pump during this time, throw out any milk you collect.

How is ioversol given?

Ioversol is given as an infusion into a vein or artery. A healthcare provider will give you this injection.

Drink extra fluids before and after your radiologic test. Ioversol can cause you to get dehydrated, which can lead to dangerous effects on your kidneys. Follow your doctor's instructions about the types and amount of fluids you should drink before and after your test.

Older adults may need special care to avoid becoming dehydrated. Your kidney function may need to be checked after you have received ioversol.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when ioversol is injected.

Some people receiving ioversol have had delayed reactions 30 to 60 minutes after injection. Your caregivers will watch you during this time to make sure you do not have unwanted side effects or delayed reactions.

Ioversol can cause unusual results with certain medical tests for up to 16 days after you receive this medicine. For up to 8 weeks after you receive ioversol, your body may not respond as well as usual to radioactive iodine thyroid treatment. Tell any doctor who treats you that have recently received ioversol.

What happens if I miss a dose?

Since ioversol is used only during your radiologic test, you will not be on a dosing schedule.

What happens if I overdose?

Since this medicine is given by a healthcare professional in a medical setting, an overdose is unlikely to occur. You will be watched closely for any signs of an overdose.

What should I avoid after receiving ioversol?

Do not allow yourself to become dehydrated during the first few days after receiving ioversol. Call your doctor if you have any vomiting or diarrhea during this time. Follow your doctor's instructions about the types and amount of fluids you should drink.

What are the possible side effects of ioversol?

Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).

Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes.

Some of the side effects of ioversol can occur up to 24 hours after you receive the medication.

Tell your caregivers or call your doctor at once if you have:

  • trouble breathing;
  • a light-headed feeling, like you might pass out;
  • slow heartbeats;
  • unexplained muscle pain, tenderness, or weakness;
  • a skin rash;
  • pain, bleeding, or skin changes where the injection was given;
  • sudden numbness or weakness (especially on one side of the body), problems with vision or speech;
  • chest pain or pressure, pain spreading to your jaw or shoulder; or
  • kidney problems --little or no urination, swelling in your feet or ankles, feeling tired or short of breath.

Side effects may be more likely in older adults.

Common side effects may include:

  • fever; or
  • nausea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect ioversol?

Tell your doctor about all your current medicines, especially:

  • diabetes medicine that contains metformin (Glucophage, Glucovance, Actoplus Met, PrandiMet, Avandamet, Kombiglyze, Janumet, Kazano, Invokamet, Jentadueto, Xigduo, Synjardy, Metaglip, and others).

This list is not complete. Other drugs may affect ioversol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.

Where can I get more information?

Your doctor or pharmacist can provide more information about ioversol.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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